Domenico Ghirlandaio’s "Birth of Mary" is a large fresco in the Tornabuoni Chapel of Santa Maria Novella in Florence, painted around 1485–1490. It shows the moment aafter Anne has given birth to Mary, set not in biblical Palestine but in what looks like an elegant late-15th-century Florentine bedroom. Anne, the mother of Mary, reclines in a grand wooden bed, propped up against rich blue textiles, while attendants bustle around her.